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Publications

5 selected publications:

1)        Ueffing N, Schuster M, Keil E, Schulze-Osthoff K, Schmitz I. Upregulation of c-FLIPshort by NFAT contributes to apoptosis resistance of short-term activated T cells. Blood 2008 Aug 1;112(3):690-8.

2)        Schuster M, Glauben R, Plaza-Sirvent C, Schreiber L, Annemann M, Floess S, Kühl AA, Clayton LK, Sparwasser T, Schulze-Osthoff K, Hühn J, Siegmund B, Pfeffer K, Schmitz I. IkBNS Protein Mediates Regulatory T Cell Development via Induction of the Foxp3 Transcription Factor. Immunity 2012 Dec 14;37(6):998-1008.

3)        Neumann Y, Bruns SA, Rohde M, Prajsnar TK, Foster SJ, Schmitz I. Intracellular Staphylococcus aureus is targeted by selective autophagy and escapes by Mapk14-mediated inhibition of lysosomal fusion. Autophagy. 2016 Nov;12(11):2069-2084.

4)        Plaza-Sirvent C, Schuster M, Neumann Y, Heise U, Pils MC, Schulze-Osthoff K, Schmitz I. c-FLIP expression in Foxp3-expressing cells is essential for survival of regulatory T cells and prevention of autoimmunity. Cell Reports. 2017 Jan 3;18(1):12-22.

5)        Bank U, Deiser K, Plaza-Sirvent C, Osbelt L, Witte A, Knop L, Labrenz R, Jänsch R, Richter F, Biswas A, Zenclussen AC, Vivier E, Romagnani C, Kühl AA, Dunay IR, Strowig T, Schmitz I*, Schüler T*. c-FLIP is crucial for IL-7/IL-15-dependent NKp46(+) ILC development and protection from intestinal inflammation in mice. Nat Commun. 2020 Feb 26;11(1):1056. * = both authors contributed equally to this work

Publications of the last 5 years:
2024

Mühlen S, Heroven AK, Elxnat B, Kahl S, Pieper DH, Dersch P. Infection and antibiotic-associated changes in the fecal microbiota of C. rodentium ϕstx2dact-infected C57BL/6 mice. Antimicrob Agents Chemother. 2024 May 2;68(5):e0005724. doi: 10.1128/aac.00057-24. 

Köhler A, Geiselhöringer AL, Kolland D, Kreft L, Wichmann N, Hils M, Pasztoi M, Zurkowski E, Vogt J, Kübelbeck T, Biedermann T, Schmitz I, Hansen W, Kramer D, Gaida MM, Schmidt-Weber CB, Hoevelmeyer N, Ohnmacht C. The atypical IκB family member Bcl3 determines differentiation and fate of intestinal RORγt+ regulatory T-cell subsets. Mucosal Immunol. 2024 Apr 23:S1933-0219(24)00039-4. doi: 10.1016/j.mucimm.2024.04.002

Weidinger D, Jacobsen J, Alish D, Uebner H, Heinen N, Greune L, Westhoven S, Jamal Jameel K, Krosbein J, Pfaender S, Taube C, Reuter S, Peters M, Hatt H, Knobloch J. Olfactory receptors impact pathophysiological process of lung diseases in bronchial epithelial cells. J. Eur J Cell Biol. 2024 Mar 30;103(2):151408. doi: 10.1016/j.eicb.2024.151408.

Reinehr S, Wulf J, Theile J, Schulte KK, Peters M, Fuchshofer R, Dick HB, Joachim SC. In a novel autoimmune and high-pressure glaucoma model a complex immune response is induced. Front Immunol. 2024 Mar 7;15:1296178

2023

Schmidt H, Raj T, O'Neill TJ, Muschaweckh A, Giesert F, Negraschus A, Hoefig KP, Behrens G, Esser L, Baumann C, Feederle R, Plaza-Sirvent C, Geerlof A, Gewies A, Isay SE, Ruland J, Schmitz I, Wurst W, Korn T, Krappmann D, Heissmeyer V. Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2309205120. doi: 10.1073/pnas.2309205120.

Schmitz I, Mühlen S. An innate immune sensor wandering around - NOD1 promotes cell migration via non-canonical signaling. FEBS J. 2023 Sep 21. doi: 10.1111/febs.16952

Simsek A, Bessen C, Meister TL, Urlaub D, Skaletz-Rorowski A, Brockmeyer NH, Overheu O, Reinacher-Schick A, Faissner S, Watzl C, Pfaender S, Schmitz I, Potthoff A, Plaza-Sirvent C. Humoral and cellular immune responses to repeated SARS-CoV-2 infection and vaccination in an individual living with HIV. J Eur Acad Dermatol Venereol. 2023 Mar 13. doi: 10.1111/jdv.19036.

Wacker M, Ball A, Beer H-D, Schmitz I, Borucki K, Azizzadeh F, Scherner M, Awad G, Wippermann J, Veluswamy P. Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients. Int J Mol Sci. 2023; 24(8):7198. doi: 10.3390/ijms24087198

Blasey N, Rehrmann D, Riebisch AK, Mühlen S. Targeting bacterial pathogenesis by inhibiting virulence-associated Type III and Type IV secretion systems. Front Cell Infect Microbiol. 2023 Jan 10;12:1065561. doi: 10.3389/fcimb.2022.1065561

2022

Frentzel S, Jeron A, Pausder A, Kershaw O, Volckmar J, Schmitz I, Bruder D. IkBNS-deficiency protects mice from fatal Listeria monocytogenes infection by blunting pro-inflammatory signature in Ly6Chigh monocytes and preventing exaggerated innate immune responses. Front Immunol. 2022 Dec 22;13:1028789. doi: 10.3389/fimmu.2022.1028789.

Heinen N, Marheinecke CS, Bessen C, Blazquez-Navarro A, Roch T, Stervbo U, Anft M, Plaza-Sirvent C, Busse S, Klöhn M, Schrader J, Vidal Blanco E, Urlaub D, Watzl C, Hoffmann M, Pöhlmann S, Tenbusch M, Steinmann E, Todt D, Hagenbeck C, Zimmer G, Schmidt WE, Quast DR, Babel N, Schmitz I, Pfaender S. In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant. Front Immunol. 2022 Dec 21;13:1062210. doi: 10.3389/fimmu.2022.1062210.

Weidinger D, Jamal Jameel K, Alisch D, Jacobsen J, B√ºrger P, Ruhe M, Yusuf F, Rohde S, Störtkuhl K, Kaufmann P, Kronsbein J, Peters M, Hatt H, Giannakis N, Knobloch J. OR2AT4 and OR1A2 counterregulate molecular pathophysiological processes of steroid-resistant inflammatory lung diseases in human alveolar macrophages. Mol Med. 2022 Dec 12;28(1):150. doi: 10.1186/s10020-022-00572-8.

Bessen C, Plaza-Sirvent C, Simsek A, Bhat J, Marheinecke C, Urlaub D, Bonowitz P, Busse S, Schumann S, Blanco EV, Skaletz-Rorowski A, Brockmeyer NH, Overheu O, Reinacher-Schick A, Faissner S, Watzl C, Pfaender S, Potthoff A, Schmitz I. Impact of SARS-CoV-2 vaccination on systemic immune responses in people living with HIV. Front Immunol. 2022 Dec 2;13:1049070. doi: 10.3389/fimmu.2022.1049070.

Faissner S, Heitmann N, Rohling R, Ceylan U, Bongert M, Plaza-Sirvent C, Marheinecke C, Pedreiturria X, Ayzenberg I, Hellwig K, Schmitz I, Pfaender S, Gold R. Preserved T-cell response in anti-CD20-treated multiple sclerosis patients following SARS-CoV-2 vaccination. Ther Adv Neurol Disord. 2022 Dec 9;15:17562864221141505. doi: 10.1177/17562864221141505.

Papaxenopoulou LA, Zhao G, Khailaie S, Katsoulis-Dimitriou K, Schmitz I, Medina E, Hatzikirou H, Meyer-Hermann M. In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo. iScience. 2022 Nov 8;25(12):105522. doi: 10.1016/j.isci.2022.105522.

Verheyen M, Puschkarow M, Gnipp S, Koesling D, Peters M, Mergia E. The differential roles of the two NO-GC isoforms in adjusting airway reactivity. Am J Physiol Lung Cell Mol Physiol. 2022 Oct 1;323(4):L450-L463. doi: 10.1152/ajplung.00404.2021.

Thon P, Rump K, Knorr A, Dyck B, Ziehe D, Unterberg M, Nowak H, Bergmann L, Wolf A, Bazzi M, Orlowski J, Peters M, Zarbock A, Brenner T, Adamzik M, Rahmel T, Koos B. The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis. Cells. 2022 Sep 27;11(19):3020. doi: 10.3390/cells11193020.

Faissner S, Heitmann N, Plaza-Sirvent C, Trendelenburg P, Ceylan U, Motte J, Bessen C, Urlaub D, Watzl C, Overheu O, Reinacher-Schick A, Hellwig K, Pfaender S, Schmitz I, Gold R. Immune response in ofatumumab treated multiple sclerosis patients after SARS-CoV-2 vaccination. Front Immunol. 2022 Aug 31;13:980526. doi: 10.3389/fimmu.2022.980526.

Zhang H, Quintana J, Ütkür K, Adrian L, Hawer H, Mayer K, Gong X, Castanedo L, Schulten A, Janina N, Peters M, Wirtz M, Brinkmann U, Schaffrath R, Krämer U. Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis. Nat Commun. 2022 Jul 11;13(1):4009. doi: 10.1038/s41467-022-31712-7.

Dwyer JR, Racine JJ, Chapman HD, Quinlan A, Presa M, Stafford GA, Schmitz I, Serreze DV. Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells. J Immunol. 2022 Jul 15;209(2):227-237. doi: 10.4049/jimmunol.2100558.

Schiffer M, Peters K, Peters M. Comparison of airway remodeling in two different endotypes of allergic asthma. Int Arch Allergy Immunol. 2022;183(7):714-725.

Zhang H, Quintana J, Ütkür K, Adrian L, Hawer H, Mayer K, Gong X, Castanedo L, Schulten A, Janina N, Peters M, Wirtz M, Brinkmann U, Schaffrath R, Krämer U. Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis. Nat Commun. 2022 Jul 11;13(1):4009. doi: 10.1038/s41467-022-31712-7.

Kästle M, Merten C, Hartig R, Plaza-Sirvent C, Schmitz I, Bommhardt U, Schraven B, Simeoni L. Y192 within the SH2 Domain of Lck Regulates TCR Signaling Downstream of PLC-γ1 and Thymic Selection. Int J Mol Sci. 2022 Jun 30;23(13):7271. doi: 10.3390/ijms23137271.

Schmitz I. Gadd45 Proteins in Immunity 2.0. Adv Exp Med Biol. 2022, May 04, 1360:69-86. doi: 10.1007/978-3-030-94804-7_5.

Bhat J*#, Placek K*, Faissner S. Contemplating dichotomous nature of gamma delta T cells for immunotherapy. Front Immunol. 2022, Apr 22, 13:894580. doi: 10.3389/fimmu.2022.894580. # corresponding author and * both authors contributed equally to this work.

Bachmann L, Gallego Villarejo L, Heinen N, Marks D, Peters M, Müller T. Gene-edited fluorescent cerebral organoids to study human brain function and disease. CRISPR J. 2022 Feb 22;5(1):53-65.

2021

Klionsky DJ, …, Schmitz I, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280.

Riebisch AK, Mühlen S, Beer YY, Schmitz I. Autophagy - A Story of Bacteria Interfering with the Host Cell Degradation Machinery. Pathogens. 2021 Jan 22;10(2):110. doi: 10.3390/pathogens10020110.

Funke L, Gnipp S, Ahrens M, Eisenacher M, Peters M, Sitek B, Bracht T. Quantitative analysis of proteome dynamics in a mouse model of asthma. Clin. Exp. Allergy. 2021 Feb 7. doi: 10.1111/cea.13843. Online ahead of print.

Bannewitz C, Lenz-Habijan T, Lentz J, Peters M, Trösken V, Siebert S, Weber S, Theisen W, Henkes H, Monstadt H. Evaluation of Antithrombogenic pHPC on CoCr Substrates for Biomedical Applications. Coatings 2021, 11(1), 93.

Krumb M, Jäger M, Voss A, Immig L, Peters K, Kowalczyk D, Bufe A, Opatz T, Holst O, Vogel C, and Peters M. Total Synthesis of a Partial Structure from Arabinogalactan and its Application for AllergyPrevention. Chem. Eur. J. 2021, 27:928 –933.

Chaoprasid P*, Lukat P*, Mühlen S*, Heidler T, Gazdag EM, Dong S, Bi W, Rüter C, Kirchenwitz M, Steffen A, Jänsch L, Stradal TEB, Dersch P*, Blankenfeldt W* (2021). Crystal structure of full-length cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication EMBO J. Jan 7:e105202. doi: 10.15252/embj.2020105202. * equal contribution

Peters K and Peters M. The role of lectin receptors and their ligands in controlling allergic inflammation. Front Immunol. 2021 Apr 30; 12:635411. doi: 10.3389/fimmu.2021.635411.

Carmo-Fernandes A, Puschkarow M, Peters K, Gnipp S, Peters M. The Pathogenic Role of Smooth Muscle Cell-Derived Wnt5a in a Murine Model of Lung Fibrosis. Pharmaceuticals. 2021; 14(8):755. https://doi.org/10.3390/ph14080755

Plaza-Sirvent C, Zhao B, Bronietzki AW, Pils MC, Tafrishi N, Schuster M, Strowig T, Schmitz I. A Central Role for Atg5 in Microbiota-Dependent Foxp3+ RORγt+ Treg Cell Preservation to Maintain Intestinal Immune Homeostasis. Front Immunol. 2021 12:705436. doi: 10.3389/fimmu.2021.705436.

Stiehm M and Peters M. Specific immunotherapy in a murine model of grass pollen (Phl p5) allergy. Front Allergy. 2021 Dec 16;2:777545.

Carriche GM, Almeida L, Stüve P, Velasquez L, Dhillon-LaBrooy A, Roy U, Lindenberg M, Stowig T, Plaza-Sirvent C, Schmitz I, Lochner M, Simon AK, Sparwasser T. Regulating T-cell differentiation through the polyamine spermidine. J Allergy Clin Immunol. 2021 Jan;147(1):335-348.e11. doi:10.1016/j.jaci.2020.04.037

2020

Bonifacius A, Goldmann O, Floess S, Holtfreter S, Robert PA, Nordengrün M, Kruse F, Lochner M, Falk CS, Schmitz I, Bröker BM, Medina E, Huehn. Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses. J. Front Immunol. 2020 Aug 7;11:1579.

Shah A, Plaza-Sirvent C, Weinert S, Buchbinder JH, Lavrik IN, Mertens PR, Schmitz I*, Lindquist JA*. YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation. Cancers (Basel). 2020 Aug 5;12(8):E2188. * equal contribution

Wahlicht T, Vièyres G, Bruns SA, Meumann N, Büning H, Hauser H, Schmitz I, Pietschmann T, Wirth D. Controlled Functional Zonation of Hepatocytes In Vitro by Engineering of Wnt Signaling. ACS Synth Biol. 2020 Jul 17;9(7):1638-1649.

Carriche GM, Almeida L, Stüve P, Velasquez L, Dhillon-LaBrooy A, Roy U, Lindenberg M, Strowig T, Plaza-Sirvent C, Schmitz I, Lochner M, Simon AK, Sparwasser T. Regulating T-cell differentiation through the polyamine spermidine. J Allergy Clin Immunol. 2020 May 11:S0091-6749(20)30637-0.

Bank U, Deiser K, Plaza-Sirvent C, Osbelt L, Witte A, Knop L, Labrenz R, Jänsch R, Richter F, Biswas A, Zenclussen AC, Vivier E, Romagnani C, Kühl AA, Dunay IR, Strowig T, Schmitz I*, Schüler T*. c-FLIP is crucial for IL-7/IL-15-dependent NKp46(+) ILC development and protection from intestinal inflammation in mice. Nat Commun. 2020 Feb 26;11(1):1056. * = both authors contributed equally to this work

Luu M, Romero R, Bazant J, Abass E, Hartmann S, Leister H, Fischer F, Mahdavi R, Plaza-Sirvent C, Schmitz I, Steinhoff U, Visekruna A. The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium. Eur J Immunol.  2020 Feb;50(2):292-294.

Mundorf A, Rommel S, Verheyen M, Mergia E, Peters M, Freund N. Cigarette smoke exposure has region-specific effects on GDAP1 expression in mouse hippocampus. Psychiatry Res. 2020 May 7;289:112979.

Twittenhoff C, Heroven AK, Mühlen S, Dersch P, and Narberhaus F.(2020). An RNA thermometer dictates production of a secreted bacterial toxin.  PLoS Pathogens 16(1):e1008184. doi: 10.1371/journal.ppat.1008184.

Mühlen S, Ramming I, Pils MC, Koeppel M, Glaser J, Leong J, Flieger A, Stecher B, Dersch P (2020). Identification of antibiotics that diminish disease in a murine model of enterohemorrhagic Escherichia coli infection. Antimicrob Agents Chemother. 64(4):e02159-19. doi: 10.1128/AAC.02159-19.

Osbelt L, Thiemann S, Smit N, Lesker TR, Schmidt-Hohagen K, Pils M, Mühlen S, Dersch P, Hiller K, Schlüter D, Neumann-Schaal M and Strowig T. (2020). Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production. PLoS Pathogens 16(3):e1008448. doi: 10.1371/journal.ppat.1008448.

Mühlen S, and Dersch P. (2020). Treatment strategies for infections with Shiga toxin-producing Escherichia coli. Front in Cell Infect Microbiol. 10:169. doi: 10.3389/fcimb.2020.00169.

Riebisch A, Mühlen S. Attaching and effacing pathogens: the effector ABC of immune subversion. Future Microbiol. 2020 Jul;15:945-958. doi: 10.2217/fmb-2019-0274.

2019

Schuster M, Plaza-Sirvent C, Visekruna A, Huehn J, Schmitz I. Generation of Foxp3(+)CD25(-) Regulatory T-Cell Precursors Requires c-Rel and IκB(NS). Front Immunol. 2019 Jul 10;10:1583.

Luebke T, Schwarz L, Beer YY, Schumann S, Misterek M, Sander FE, Plaza-Sirvent C, Schmitz I. c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma. Cell Death Dis. 2019 May 16;10(6):384.

Frentzel S, Katsoulis-Dimitriou K, Jeron A, Schmitz I*, Bruder D*. Essential role of IκB(NS) for in vivo CD4(+) T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice. Eur J Immunol. 2019 Sep;49(9):1391-1398.  * = both authors contributed equally to this work

Lowinus T, Heidel FH, Bose T, Nimmagadda SC, Schnöder T, Cammann C, Schmitz I, Seifert U, Fischer T, Schraven B, Bommhardt U. Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of K(v)1.3 potassium channels, AKT and ERK1/2 signaling. Cell Commun Signal. 2019 Jan 16;17(1):5.

Peters M, Peters K, Bufe A. Regulation of lung immunity by dendritic cells: Implications for asthma, chronic obstructive pulmonary disease and infectious disease. Innate Immun. 2019; 25(6):326-36.

Henkes H, Bhogal P, Aguilar Pérez M, Lenz-Habijan T, Bannewitz C, Peters M, Sengstock C, Ganslandt O, Lylyk P, Monstadt H. Anti-thrombogenic coatings for devices in neurointerventional surgery: Case report and review of the literature. Interv Neuroradiol. 2019 Dec; 25(6):619-627.

Peters M. A patent on the synthesis of arabinooligosaccharides for regulation of immune responses in the lung. Allergy. 2019 Dec;74(12):2547-2549.

Knobloch J, Panek S, Yanik S, Jameel KJ, Bendella Z, Jungck D, Bürger P, Bülthoff E, Struck B, Giannakis N, Rupp J, Kronsbein J, Peters M, Koch A. The monocyte-dependent immune response to bacteria is suppressed in smoking-induced COPD. J Mol Med (Berl). 2019 Jun; 97(6):817-828.

Fettel J, Kühn B, Guillen NA, Sürün D, Peters M, Bauer R, Angioni C, Geisslinger G, Schnütgen F, Meyer Zu Heringdorf D, Werz O, Meybohm P, Zacharowski K, Steinhilber D, Roos J, Maier TJ. Sphingosine-1-phosphate (S1P) induces potent anti-inflammatory effects in vitro and in vivo by S1P receptor 4-mediated suppression of 5-lipoxygenase activity. FASEB J. 2019 Feb;33(2):1711-1726.

2018

Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV. A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8(+) T Cells in NOD Mice. J Immunol. 2018 Oct 1;201(7):1907-1917.

Gnipp S, Mergia E, Puschkarow M, Bufe A, Koesling D and Peters M.  Nitric oxide dependent signaling via cyclic GMP in dendritic cells regulates migration and T-cell polarization. Sci Rep. 2018 Jul 20;8(1):10969.

Lenz-Habijan T, Bhogal P, Peters M, Bufe A, Martinez Moreno R, Bannewitz C, Monstadt H, Henkes H. Hydrophilic stent coating inhibits platelet adhesion on stent surfaces: initial results in vitro. Cardiovasc Intervent Radiol. 2018 Nov; 41(11):1779-1785.

Roos J*, Peters M*, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscato E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ. Drug-mediated intracellular donation of nitric oxide potently inhibits 5-lipoxygenase: a possible key to future anti-leukotriene therapy. Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. * = both authors contributed equally to this work

Lang C, Prager R, Fruth A, Tietze E, Holland G, Laue M, Mühlen S, Dersch P and Flieger A (2018). Widely distributed novel type of pili associated with a Shiga-toxigenic and enteroaggregative E. coli hybrid is essential for aggregative adherence. Emerg Microbes Infect. 2018 Dec 5;7(1):203.

2017

Plaza-Sirvent C, Schuster M, Neumann Y, Heise U, Pils MC, Schulze-Osthoff K, Schmitz I. c-FLIP expression in Foxp3-expressing cells is essential for survival of regulatory T cells and prevention of autoimmunity. Cell Reports. 2017 Jan 3;18(1):12-22.

Schuster M, Plaza-Sirvent C, Matthies AM, Heise U, Jeron A, Bruder D, Visekruna A, Huehn J, Schmitz I. c-REL and IkBNS govern common and independent steps of regulatory T-cell development from novel CD122-expressing pre-precursors. J Immunol. 2017 Aug 1;199(3):920-930.

Chaudhry AZ, Kasmapour B, Plaza-Sirvent C, Bajagic M, Casalegno Garduno R, Borkner L, Lenac Rovis T, Scrima A, Jonjic S, Schmitz I, Cicin-Sain L. UL36 rescues apoptosis inhibition and in vivo replication of a chimeric MCMV lacking the M36 gene. Frontiers Cell Infect Microbiol. 14 July 2017 https://doi.org/10.3389/fcimb.2017.00312

Zhao G, Wirth D, Schmitz I, Meyer-Herrmann M. Mathematical modeling of the impact of insulin secretion dynamics on selective hepatic insulin resistance. Nat Commun. 2017 Nov 8;8(1):1362.

Peters M, Bonowitz P, Bufe A. A Bioassay for the Determination of Lipopolysaccharides and Lipoproteins. Methods Mol Biol. 2017;1600:143-150.

Dersch P, Khan MA, Mühlen S, Görke B. Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets. (2017) Front. Microbiol. 2017 May 5;8:803.

Creuzburg K, Giogha C, Wong Fok Lung T, Scott NE, Mühlen S, Hartland EL and Pearson JS (2017). The Type III effector NleD from enteropathogenic E. coli differentiates between host substrates p38 and JNK. Infect Immun. 2017 Jan 26;85(2).

Pearson JS*, Giogha C*, Mühlen S, Nachbur U, Phi CLL, Zhang Y, Hildebrand J, Oates CV, Wong Fok Lung T, Ingle D, Dagley L, Bankovacki A, Petrie E, Schroeder GN, Crepin V, Frankel G, Masters S, Vince J, Murphy J, Sunde M, Webb AI, Silke J, and Hartland EL (2017). A bacterial cysteine protease effector cleaves RHIM proteins to block necroptosis and inflammation. Nat Microbiol. 2017 Jan 13;2:16258.